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The stem cells infusion consists in a common intravenous administration, in which the CD34+ cells are introduced in the bloodstream and they are going to colonize the recipient BM in a process termed engraftment. Before the infusion, the graft could be manipulated in vitro for example: decreasing the number of T cells by reducing the risks of the post-transplant complication as the GvHD; or purifying it from the red cells just in the case in which the donor-patient are incompatible for the blood group
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